Detalhe da pesquisa
1.
Targeting the mutant PIK3CA gene by DNA-alkylating pyrrole-imidazole polyamide in cervical cancer.
Cancer Sci
; 112(3): 1141-1149, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33377228
2.
Hydrophobic structure of hairpin ten-ring pyrrole-imidazole polyamides enhances tumor tissue accumulation/retention in vivo.
Bioorg Med Chem
; 26(9): 2337-2344, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29622411
3.
Use of DNA-alkylating pyrrole-imidazole polyamides for anti-cancer drug sensitivity screening in pancreatic ductal adenocarcinoma.
Cancer Med
; 12(5): 5821-5832, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36262061
4.
Targeting anaplastic lymphoma kinase (ALK) gene alterations in neuroblastoma by using alkylating pyrrole-imidazole polyamides.
PLoS One
; 16(9): e0257718, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34591871
5.
Estimating genome-wide off-target effects for pyrrole-imidazole polyamide binding by a pathway-based expression profiling approach.
PLoS One
; 14(4): e0215247, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30964912
6.
Direct Targeting of MYCN Gene Amplification by Site-Specific DNA Alkylation in Neuroblastoma.
Cancer Res
; 79(4): 830-840, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30584073
7.
Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome.
PLoS One
; 11(10): e0165581, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27798693
8.
Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate.
Nat Commun
; 6: 6706, 2015 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25913614